Ingredients
Ginger Root Extract (1,000 mg) Targets the serotonin signaling that triggers nausea and supports gastric emptying.
DGL Licorice Root Extract (400 mg) Protects the stomach lining and addresses the reflux caused by slowed digestion.
Ginger Root Powder (300 mg) Full-spectrum botanical support alongside the standardized extract.
Peppermint Leaf Extract (100 mg) Relaxes smooth muscle to ease cramping and gastric tension.
Vitamin B6 (25 mg) The active form of B6, supporting the neurotransmitters that regulate the nausea response.
Other Ingredients: HPMC vegetable capsule, rice hull concentrate.
Free from: Dairy, soy, gluten, eggs, nuts, fish, shellfish, sesame, artificial colors, and fillers.
How to use
For acute relief: Take 3 capsules at the first sign of nausea, before injection day, or anytime you need fast-acting support. Most users feel relief within 30 to 60 minutes.
For ongoing support: Can be taken up to twice daily during titration weeks or periods of increased need.
Best practices:
- Take with or without food
- Drink plenty of water
- Keep on hand for unexpected nausea episodes
- Pair with a small snack if taking on an empty stomach makes you feel worse
Storage: Store in a cool, dry place. Keep out of direct sunlight to preserve ingredient potency.
When to consult your doctor: If you are pregnant, nursing, taking blood thinners, or have a medical condition, talk with your healthcare provider before use.
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WHAT IT IS
The first nausea support formula for GLP-1 users.
Nausea Defense is a clean, single-purpose formula you reach for on the days your stomach is unsettled. Built on ingredients with a long history in digestive support, dosed at levels you can actually feel, without the drowsiness.
Made for GLP-1 Users
GLP-1 nausea isn't motion sickness. It's caused by slowed gastric emptying, reflux, and gut-brain signaling unique to these medications. Preserv+ Nausea Defense was formulated specifically for this pathway, with ingredients that address the actual mechanism rather than a generic nausea masking.
Fast Acting Relief
Clinical-dose ginger and active B6 work within 30 to 60 minutes. Our formula targets the specific pathways that drive GLP-1 nausea rather than just masking the feeling, so the relief is real and noticeable, not subtle.
Non-Drowsy Formula
Unlike OTC nausea products that rely on antihistamines like Dramamine and Bonine, Preserv+ Nausea Defense uses botanical ingredients with no sedating effects. Take it before work, before driving, or anytime you need to function clearly.
Safe for Daily Use
Every ingredient is dosed within researched safe ranges for ongoing use. While we recommend taking it as needed when nausea hits, the formula is designed so you can also take it during titration weeks or any period of increased need without concern.
THE PROOF
From the people who needed it most.
"I'd take my Ozempic shot Saturday night and used to spend all of Sunday lying on the couch trying not to throw up. Now I take this 30 minutes before my shot and the nausea doesn't hit!!"
"Tried Dramamine when the nausea got bad and it knocked me out. I have two kids and a job. I can't be drowsy all day. Preserv+ gives me fast relief without putting me to sleep."
"My first month on Mounjaro almost made me quit, the nausea was so unbearable. After a dose of Preserv+ I noticed I could eat breakfast again without forcing it down. Worth every penny."
"Seriously, this stuff works SO well. and I love that I can take it daily as needed without feeling drowsy afterwards. I got the 3 pack so I can keep one at home, in my car, and at work."
"Every dose bump used to knock me down for days. Now I start Preserv+ a few days before my increase and the transition is so much smoother. It's been a game changer for titration."
"It didn't eliminate my nausea completely, but it took it from a 9 to a 4. That difference is better than everything else I've tried. I'm down 22 pounds and still on Wegovy because of this."
of users experienced reduced nausea.
said they felt relief within 30 minutes.
Reported more comfortable titration weeks.
*based on a survey conducted in january 2025 involving 100 users who had been taking Preserv consistently for 90 days.
WHATS INSIDE
Clinical doses of ingredients that work.
Every ingredient in Preserv+ Nausea Defense earns its place. Clinical doses. Standardized extracts. Sourced from suppliers we'd trust with our own bodies. Formulated for GLP-1 Users.
Ginger Root Extract
Ginger's active compounds work through multiple nausea pathways by modulating serotonin signal... read more
Ginger's active compounds work through multiple nausea pathways by modulating serotonin signals, supporting gastric emptying, and calming gut inflammation. Most supplements use 200-500mg of unstandardized ginger. We deliver the dose that clinical research supports.
read less
Ginger Root Powder
While the extract delivers concentrated gingerols, the whole root contains hundreds of support... read more
While the extract delivers concentrated gingerols, the whole root contains hundreds of supporting compounds such as shogaols, paradols, and essential oils that contribute to ginger's full effect. The combination gives you both the clinical dose and the complete botanical profile.
read less
DGL Licorice Extract
GLP-1 medications slow gastric emptying, exposing your stomach to acid for longer periods. DGL... read more
GLP-1 medications slow gastric emptying, exposing your stomach to acid for longer periods. DGL stimulates the mucus layer that defends against that acid and addresses the root cause of reflux, burning, and the sulfur burps that trigger nausea.
read less
Peppermint Extract
GLP-1 nausea often comes with cramping and tension as your stomach responds to slowed emptying... read more
GLP-1 nausea often comes with cramping and tension as your stomach responds to slowed emptying. Peppermint's menthol binds to TRPM8 receptors and relaxes smooth muscle in the GI tract to ease the spasms that amplify the nausea sensation. The result: less tension, less discomfort, and a stomach that feels at ease.
read less
Vitamin B6 (P5P)
The active form of B6, already converted and ready for your body to use. B6 acts as a cofactor... read more
The active form of B6, already converted and ready for your body to use. B6 acts as a cofactor for the neurotransmitters that regulate the brain's nausea response, modulating the chemoreceptor trigger zone that initiates that "I'm going to be sick" feeling. We use P5P specifically for fast-acting acute relief.
read less
Ginger Root Extract
Ginger's active compounds work through multiple nausea pathways by modulating serotonin signal... read more
Ginger's active compounds work through multiple nausea pathways by modulating serotonin signals, supporting gastric emptying, and calming gut inflammation. Most supplements use 200-500mg of unstandardized ginger. We deliver the dose that clinical research supports.
read less
Ginger Root Powder
While the extract delivers concentrated gingerols, the whole root contains hundreds of support... read more
While the extract delivers concentrated gingerols, the whole root contains hundreds of supporting compounds such as shogaols, paradols, and essential oils that contribute to ginger's full effect. The combination gives you both the clinical dose and the complete botanical profile.
read less
DGL Licorice Extract
GLP-1 medications slow gastric emptying, exposing your stomach to acid for longer periods. DGL... read more
GLP-1 medications slow gastric emptying, exposing your stomach to acid for longer periods. DGL stimulates the mucus layer that defends against that acid and addresses the root cause of reflux, burning, and the sulfur burps that trigger nausea.
read less
Peppermint Extract
GLP-1 nausea often comes with cramping and tension as your stomach responds to slowed emptying... read more
GLP-1 nausea often comes with cramping and tension as your stomach responds to slowed emptying. Peppermint's menthol binds to TRPM8 receptors and relaxes smooth muscle in the GI tract to ease the spasms that amplify the nausea sensation. The result: less tension, less discomfort, and a stomach that feels at ease.
read less
Vitamin B6 (P5P)
The active form of B6, already converted and ready for your body to use. B6 acts as a cofactor... read more
The active form of B6, already converted and ready for your body to use. B6 acts as a cofactor for the neurotransmitters that regulate the brain's nausea response, modulating the chemoreceptor trigger zone that initiates that "I'm going to be sick" feeling. We use P5P specifically for fast-acting acute relief.
read lessFAQ
About the Product
Preserv+ Nausea Defense is a daily-safe capsule formulated specifically for adults taking GLP-1 medications (Ozempic, Wegovy, Mounjaro, Zepbound, and compounded semaglutide/tirzepatide). It contains five clinically-dosed ingredients (ginger root extract, ginger root powder, DGL licorice, peppermint leaf, and active B6) designed to address the specific way GLP-1 medications cause nausea.
Adults currently taking GLP-1 medications who experience nausea, especially during titration weeks (when starting or increasing dose) and on injection days. If you're new to GLP-1s, in active titration, or have ongoing nausea episodes that interfere with your day, this product was built for you.
No. Preserv+ Nausea Defense is a dietary supplement, not a prescription medication. It does not contain semaglutide, tirzepatide, or any GLP-1 receptor agonist drugs. It is designed to support people who are already taking these medications by helping manage nausea (one of the most common side effects).
Dramamine and Bonine contain antihistamines (dimenhydrinate or meclizine) that cause significant drowsiness and are designed for occasional motion sickness, not daily use. Preserv+ uses botanical and vitamin ingredients with no drowsiness, is safe for ongoing use during your GLP-1 journey, and is formulated for the specific way GLP-1 medications cause nausea rather than motion sickness.
How to Use
Take 3 capsules at the first sign of nausea, before injection day, or anytime you need fast-acting support. You can take it on an empty stomach or with food.
Most users feel relief within 30 to 60 minutes. Individual results vary based on metabolism, severity of symptoms, and whether you take it preventively (before nausea hits) or reactively (after nausea starts).
Yes. All ingredients are dosed within safe ranges for ongoing use. Many users take it daily during their first months on a GLP-1 medication or during titration weeks when nausea is most frequent.
We recommend taking up to two servings (6 capsules total) per day during periods of intense need. For most users, one serving daily is sufficient.
For acute relief, take it when you feel nausea coming on. For preventive use, many customers take it 30 minutes before their injection or with their morning routine. There's no single "right" time, just take it when you need it.
Either works. If taking on an empty stomach causes additional discomfort (this is rare with Preserv+), pair it with a small snack.
Safety and Compatibility
Yes. Preserv+ Nausea Defense was designed specifically for adults taking GLP-1 medications and does not interfere with their mechanism. That said, if you have any health concerns, we recommend consulting your healthcare provider before adding any supplement to your routine.
Yes, with one important note: do not combine with other supplements that contain Vitamin B6. Preserv+ contains 25 mg of B6, and stacking with B-complex vitamins, multivitamins, or energy drinks fortified with B6 could push your daily intake above safe levels.
The ingredients in Preserv+ are generally safe, but ginger has mild blood-thinning effects. If you take prescription blood thinners (warfarin, Xarelto, Eliquis) or take aspirin daily, consult your doctor before use. People with severe acid reflux (GERD) should also consult their doctor, as peppermint can occasionally worsen these conditions.
The ingredients in Preserv+ have a long history of safe use, but we recommend consulting your healthcare provider before taking any supplement during pregnancy or breastfeeding. GLP-1 medications themselves are generally not recommended during pregnancy.
No. Unlike OTC nausea products (Dramamine, Bonine), Preserv+ contains no sedating antihistamines. You can take it before work, before driving, or anytime you need to function normally.
Preserv+ was specifically formulated for GLP-1-induced nausea. The ingredients may help with other types of nausea (pregnancy, motion sickness, post-surgical), but our formulation is optimized for the specific mechanisms behind GLP-1 nausea. We recommend products designed for those specific use cases if your nausea is not GLP-1 related.
Quality and Sourcing
Preserv+ Nausea Defense is manufactured in the United States in an FDA-registered facility operating under Current Good Manufacturing Practices (cGMP). Our manufacturer is NSF-certified and follows third-party testing protocols.
Yes. Every batch is tested by an independent laboratory for purity, potency, and contaminants including heavy metals (lead, arsenic, cadmium, mercury) and microbials. Certificates of Analysis are available on request.
Preserv+ is vegan (HPMC vegetable capsules, no animal-derived ingredients) and free from the major nine allergens: dairy, soy, gluten, eggs, nuts, fish, shellfish, and sesame. It also contains no artificial colors, flavors, or fillers.
We stand behind our formula with a 30-day money-back guarantee. If Preserv+ doesn't work for you, contact our customer support and we'll process a full refund.